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Different mechanisms of antibody-mediated neutralization of parvoviruses revealed using the Fab fragments of monoclonal antibodies

โœ Scribed by Christian D.S. Nelson; Laura M. Palermo; Susan L. Hafenstein; Colin R. Parrish

Book ID
113947122
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
685 KB
Volume
361
Category
Article
ISSN
0042-6822

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A new method for the production of monovalent Fab fragments of antibodies has been developed. Traditionally Fab fragments are produced by proteolytic digestion of antibodies in solution followed by isolation of Fab fragments. In the case of monoclonal antibodies against inactivated subunits of glyce