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Different mechanism of blockade of neuroexocytosis by presynaptic neurotoxins

โœ Scribed by O Rossetto; M Rigoni; C Montecucco


Book ID
119377797
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
299 KB
Volume
149
Category
Article
ISSN
0378-4274

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The vesicular neuroexocytosis process consists of two important steps: fusion of transmitter-loaded vesicles at release sites on the presynaptic nerve terminal membrane; followed by the release of transmitter molecules into the synaptic cleft. We previously reported that in nerve growth factor (NGF)