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Different Inducibility of Cytochrome P-4501A1 mRNA of Human and Mouse by Omeprazole in Culture Cells

โœ Scribed by H. Kikuchi; A. Hossain; I. Sagami; S. Ikawa; M. Watanabe


Book ID
115565427
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
334 KB
Volume
316
Category
Article
ISSN
0003-9861

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Recombinant DNA techniques have been used to develop Chinese hamster ovary cell lines for studying chemically induced genotoxicity. These cell lines express a specific cytochrome P450 isozyme responsible for the metabolism of polycyclic aromatic hydrocarbons and exhibit defined differences in DNA re