## Abstract A study was carried out to determine whether early viral dynamics retain prediction of the outcome of peginterferon (PEG‐IFN) and ribavirin combination therapy based on different genetic polymorphisms near the __IL28B__ gene, the strongest baseline predictor of response to this therapy.
✦ LIBER ✦
Different impact of IL28B polymorphisms on response to peginterferon-α plus ribavirin in HIV-positive patients infected with HCV subtypes 1a or 1b
✍ Scribed by Eugenia Vispo; Norma I. Rallon; Pablo Labarga; Pablo Barreiro; Jose Miguel Benito; Vincent Soriano
- Book ID
- 116632364
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 251 KB
- Volume
- 55
- Category
- Article
- ISSN
- 1386-6532
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The IL28B genotype is the most important pretreatment predictor of treatment outcome in patients with chronic hepatitis C. The impact of the rs12979860 genotype on relapse was retrospectively evaluated in genotype 1/4 patients who received response-guided therapy with peginterferon alpha-2a 180 μg/w