Different hepatitis C virus dynamics of free-virions and immune-complexes after initiation of interferon-α in patients with chronic hepatitis C
✍ Scribed by Naoki Fujita; Masahiko Kaito; Masaki Takeo; Shinichiro Horiike; Hideaki Tanaka; Jiro Ikoma; Shozo Watanabe; Yukihiko Adachi
- Book ID
- 117372066
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 241 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0168-8278
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We tested serial serum samples for hepatitis C virus RNA from patients undergoing treatment for chronic hepatitis C with interferon-a using an assay that combined reverse transcription and polymerase chain reaction. The subjects studied were 20 patients with chronic hepatitis who had serum antibody
## Abstract In interferon treatment of chronic hepatitis C patients, the biochemical and virological responses mostly parallel each other. However, some patients who show persistent ALT normalization display continued viremia after cessation of therapy. High‐density hepatitis C virus (HCV) particle