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Different fatty acid metabolism effects of (−)-Epigallocatechin-3-Gallate and C75 in Adenocarcinoma lung cancer

✍ Scribed by Joana Relat, Adriana Blancafort, Glòria Oliveras, Sílvia Cufí, Diego Haro, Pedro F Marrero, Teresa Puig


Book ID
119897339
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
292 KB
Volume
12
Category
Article
ISSN
1471-2407

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Epigallocatechin-3-gallate is a potent n
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Chemical inhibitors of fatty acid synthase (FAS) inhibit growth and induce apoptosis in several cancer cell lines in vitro and in tumor xenografts in vivo. Recently the green tea component epigallocatechin-3-gallate (EGCG) was shown to act as a natural inhibitor of FAS in chicken liver extracts. Her