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Different effects of monocarboxylates on neuronal survival and β-amyloid toxicity

✍ Scribed by XiaoNan Wang; Toshihiro Takata; Takashi Sakurai; Koichi Yokono

Book ID
109026168
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
698 KB
Volume
26
Category
Article
ISSN
0953-816X

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## Abstract Amyloid β (Aβ) is a metabolic product of Aβ precursor protein (APP). Deposition of Aβ in the brain and neuronal degeneration are characteristic hallmarks of Alzheimer's disease (AD). Aβ induces neuronal degeneration, but the mechanism of neurotoxicity remains elusive. Increasing evidenc