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Different effects of fenfluramine isomers and metabolites on extracellular 5-HIAA in nucleus accumbens and hippocampus of freely moving rats

✍ Scribed by Maria Grazia De Simoni; Zdzislaw Juraszczyk; Fabio Fodritto; Ada De Luigi; Silvio Garattini


Book ID
115881821
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
326 KB
Volume
153
Category
Article
ISSN
0014-2999

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Combined administration of the amphetamine analogs phentermine and fenfluramine (PHEN/FEN) has been used in the treatment of obesity. While these medications are thought to modulate monoamine transmission, the precise neurochemical effects of the PHEN/FEN mixture have not been extensively studied. T