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Different effects of chlorpromazine on the synthesis of proteins in cell-free systems of rat cortex, hippocampus, medulla and cerebellum

✍ Scribed by Bohumil Jakoubek; Ivan Ha´jek; Milena Buresˇová

Book ID
118866045
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
256 KB
Volume
182
Category
Article
ISSN
0006-8993

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✍ Antonella Marte; Olimpia Pepicelli; Anna Cavallero; Maurizio Raiteri; Ernesto Fe 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB

## Abstract We have characterized the various phosphodiesterases (PDE) that degrade cyclic GMP in the prefrontal cortex, hippocampus, and cerebellum using the microdialysis technique to measure in vivo extracellular cyclic GMP in awake rats. The following PDE blockers were used (100 and 1,000 μM):