4-Chloroprolines: Synthesis, conformatio
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Matthew D. Shoulders; Ilia A. Guzei; Ronald T. Raines
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Article
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2008
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Wiley (John Wiley & Sons)
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English
β 229 KB
## Abstract Collagen is an abundant, tripleβhelical protein comprising three strands of the repeating sequence: XaaβYaaβGly. (2S)βProline and (2S,4R)β4βhydroxyproline (Hyp) are common in the primary structure of collagen. Here, we use nonnatural proline derivatives to reveal determinants of collage