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Different densities of 5-HT3 receptors are labeled by [3H]quipazine, [3H]GR 65630 and [3H]geanisetron

✍ Scribed by Erik H.F. Wong; Douglas W. Bonhaus; Jeffrey A. Lee; Irene Wu; Dana N. Loury; Richard M. Eglen

Book ID
116037554
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
618 KB
Volume
32
Category
Article
ISSN
0028-3908

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Membrane-Bound and solubilized brain 5HT
Membrane-Bound and solubilized brain 5HT3 receptors: Improved radioligand binding assays using bovine area postrema or rat cortex and the radioligands 3H-Gr65630C, 3H-BRl43694, and 3H-LY278584
✍ Keith Miller; Ellen Weisberg; Paul W. Fletcher; DR. Milt Teitler πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 866 KB

Bovine area postrema tissue was used as a convenient source of tissue for studies of brain 5HT3 receptors. 5HT3 receptor density was determined to be 97 5 5 fmoVmg and 124 k 10 fmoVmg of protein using the commercially available 5HT3 radioligands, 3H-GR65630 and 3H-BRL43694, respectively. The equilib