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Different clinical severity of first episodes and recurrences of thrombotic thrombocytopenic purpura

โœ Scribed by Luca A. Lotta; Mariagabriella Mariani; Dario Consonni; Ilaria Mancini; Roberta Palla; Alberto Maino; Dragica Vucelic; Michele Pizzuti; Pier M. Mannucci; Flora Peyvandi

Book ID
108676971
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
234 KB
Volume
151
Category
Article
ISSN
0007-1048

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Increased von Willebrand factor binding
Increased von Willebrand factor binding to platelets in single episode and recurrent types of thrombotic thrombocytopenic purpura
โœ Chow, Thomas W.; Turner, Nancy A.; Chintagumpala, Murali; McPherson, Patsy D.; N ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 227 KB ๐Ÿ‘ 2 views

Extensive microvascular platelet aggregation is characteristic of thrombotic thrombocytopenic purpura (TTP). Previous studies have indicated that abnormalities of von Willebrand factor (vWf) are often present in TTP patient plasma. There has not been previously any direct evidence linking these abno