Different capacities for amino acid transport in periportal and perivenous hepatocytes isolated by digitonin/collagenase perfusion

Different signal transduction by epiderm

Different signal transduction by epidermal growth factor may be responsible for the difference in modulation of amino acid transport between fetal and adult hepatocytes

✍ S. Leoni; S. Spagnuolo; M. Marino; F. Terenzi; M. Massimi; L. Conti Devirgiliis 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 695 KB

0018.5 Rome, /ta/y 11 -'"C1-2-aminoisobutyric acid (AIB) uptake and signal transduction pattern after epidermal growth factor (EGF) stimulation were examined in freshly isolated hepatocytes from 20-day-old fetuses and 3-month-old rats. EGF induced a transient increase of AIB transport after 10 min