✦ LIBER ✦

Different adhesion types and active sensitivity of platelet subpopulations

✍ Scribed by Zhao, B.; Filler, T. J.; Rickert, C. H.; Liu, J. F.; Skholl-Engberts, A. D.; Gurevich, V.

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 885 KB
Volume: 52
Category: Article
ISSN: 0361-8609
DOI: 10.1002/(sici)1096-8652(199608)52:4<322::aid-ajh15>3.0.co;2-f

No coin nor oath required. For personal study only.

✦ Synopsis

Two different adhesion patterns of blood platelets with different sensitivity to adenosine were demonstrated by means of reflection contrast microscopy with consecutive image analysis and cell affinity chromatography. High-performance liquid chromatography revealed that thrombin-induced serotonin release of adenosine-sensitive platelets was lower than that of adenosine-resistant cells. Our results indicate platelet heterogeneity and suggest that the platelets with lower adenosine sensitivity may be actively involved in the early interaction between platelets and injured endothelium.

📜 SIMILAR VOLUMES

Hemocompatibility of treated polystyrene

Hemocompatibility of treated polystyrene substrates: Contact activation, platelet adhesion, and procoagulant activity of adherent platelets

✍ Grunkemeier, J. M. ;Tsai, W. B. ;Horbett, T. A. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 798 KB

Platelet adhesion to biomaterials is often used as an index of blood compatibility, but a more clinically relevant issue is whether the adherent platelets are able to promote clot formation (i.e., if they are in the procoagulant state). Platelets rapidly generate thrombin when they are in the procoa

Two different types of nonthrombogenic s

Two different types of nonthrombogenic surfaces: PEG suppresses platelet adhesion ATP-independently but HEMA-St block copolymer requires ATP consumption of platelets to prevent adhesion

✍ Uchida, Katsumi ;Yamato, Masayuki ;Ito, Etsuko ;Kwon, Oh Hyeong ;Kikuchi, Akihik 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 283 KB

Poly(ethylene glycol) (PEG) and a hydrophobichydrophilic microdomain structured block copolymer comprising poly(2-hydroxyethyl methacrylate) and polystyrene (HEMA-St) have been reported to show good blood compatibility owing to inhibition of platelet activation. By using a computer-assisted novel te

Differences of platelet adhesion and thr

Differences of platelet adhesion and thrombus activation on amorphous silicon carbide, magnesium alloy, stainless steel, and cobalt chromium stent surfaces

✍ Christopher Hansi; Amina Arab; Alexander Rzany; Ingo Ahrens; Christoph Bode; Chr 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 399 KB 👁 1 views

Leucocyte and platelet adhesion in diffe

Leucocyte and platelet adhesion in different layers of the small bowel during experimental total warm ischaemia and reperfusion

✍ R. J. Beuk; G.-J. Tangelder; R. L. J. G. Maassen; J. S. L. T. Quaedackers; E. He 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 400 KB 👁 1 views

Platelet adhesiveness and lipoprotein li

Platelet adhesiveness and lipoprotein lipase activity in patients with benign and malignant disease of the prostate

✍ J. M. Ham; M. Jones; D. Kemp 📂 Article 📅 1972 🏛 John Wiley and Sons 🌐 English ⚖ 327 KB 👁 2 views

Determination of Platelet-Activating Fac

Determination of Platelet-Activating Factor Acetylhydrolase Activity by Blotting, β-Radioluminescence, and Ultrahigh-Sensitivity Television Camera Detection

✍ M. Akiyama; J. Sugatani; Y. Suzuki; M. Miwa 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 469 KB

A simple method for detecting the 1-alkyl-2-[3H]-acetyl-sn-glycero-3-phosphocholine ([3H]acetyl-PAF)-hydrolyzing activity of serum proteins is described. These were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and transferred to polyvinylidene difluoride (PVDF) membranes. T