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Differences in vascular effects and removal of endothelin-1 in human lung, brain, and skeletal muscle,

✍ Scribed by E. Weitzberg; G. Ahlborg; J. M. Lundberg

Book ID
115282080
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
616 KB
Volume
13
Category
Article
ISSN
0144-5979

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Endothelin binding in human isolated lung membrane fractions revealed a single class of high affinity recognition sites with a Kd of 1.33 +/- 0.15 nM and a Bmax of 9.61 +/- 1.44 pmol/mg protein. Endothelin inhibited [125I]endothelin binding with a Ki of 1.90 +/- 0.15 nM whereas structurally unrelate