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Differences in the action of avermectin B1a on the GABAA receptor complex of mouse and rat

✍ Scribed by David M. Soderlund; Pamela M. Adams; Jeffrey R. Bloomquist

Book ID
118316361
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
407 KB
Volume
146
Category
Article
ISSN
0006-291X

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The interaction of avermectin B1, (AVM) with the y-aminobutyric acid (GABA) receptor of rat brain was studied using radioactive ligand binding and tracer ion flux assays. Avermectin potentiated the binding of [3Hlflunitrazepam and inhibited the binding of both [3H]muscimol and [35Slf-butylbicyclopho