Differences in ocular penetration of pilocarpine in rabbits of different ages
β Scribed by Ted S. Friedman; Thomas F. Patton
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 230 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0022-3549
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π SIMILAR VOLUMES
## Abstract It has previously been documented that substantially different aqueous humour drug levels are observed in rabbits of different ages when the same dose of pilocarpine is instilled into the eye. Also, it has been shown that the aqueous humour volume ratio for rabbits of different ages can
## Abstract Although drugβprotein interactions have been shown to be important in the transport of drugs into and through the eye, ageβrelated differences in ocular drugβprotein binding have not been explored. This study was designed to investigate protein binding characteristics of pilocarpine and