Kinetic properties of the Na(+)-H+ antiport in the acinar cells of the isolated, superfused mouse lacrimal gland were studied by measuring intracellular pH (pHi) and Na+ activity (aNai) with the aid of double-barreled H(+)- and Na(+)-selective microelectrodes, respectively. Bicarbonate-free solution
โฆ LIBER โฆ
Differences in nucleotide effects on intracellular pH, Na+/H+antiport activity, and ATP-binding proteins in endothelial cells
โ Scribed by Michael Cutaia; Doloretta D. Dawicki; Lisa M. Papazian; Nancy Parks; Ellen Clarke; Sharon Rounds
- Publisher
- Society for In Vitro Biology
- Year
- 1997
- Tongue
- English
- Weight
- 770 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1475-2689
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Changes in intracellular ion concentrations have been correlated with the activation of an endogenous endonuclease and thus internucleosomal DNA cleavage during apoptosis in many cell types. We investigated whether intracellular pH could play a significant role in apoptotic initiation and progressio