Differences in juvenile atherosclerosis between patients with a novel low density lipoprotein receptor mutation and other patients with familial hypercholesterolemia
β Scribed by Rubba, P.O.; Pauciullo, P.; De Simone, V.; Giannino, A.; Liguori, R.; Argiriou, A.; Marotta, G.; Carlotto, A.; Iannuzzo, G.; Lestini, A.; Faccenda, F.
- Book ID
- 118630216
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 185 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1567-5688
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Fifty St. Petersburg patients with type IIa hyperlipoproteinemia were screened for the presence of structural rearrangements in the low-density lipoprotein receptor (LDLR) gene. One novel deletion of the length about 5 kilobases (kb) was found. This deletion seems to remove completely exons 4, 5, an