## Abstract Cervical cancer is strongly associated with infection by oncogenic forms of human papillomavirus (HPV). Although most women are able to clear an HPV infection, some develop persistent infections that may lead to cancer. The determinants of persistent infection are largely unknown. We ha
Differences in HPV 16- and HPV 18 E6/E7 oncogene expression between in situ and invasive adenocarcinomas of the cervix uteri
✍ Scribed by Sabine Riethdorf; Lutz Riethdorf; Karin Milde-Langosch; Tjoung-Won Park; Thomas Löning
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 666 KB
- Volume
- 437
- Category
- Article
- ISSN
- 1432-2307
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## Abstract Human papillomavirus (HPV) infection is associated with cervical cancer. The E2 and E1 papillomavirus proteins are expressed at the early stage of infection and regulate DNA replication. The E2 protein activates and represses transcription from different HPVs promoters. At some stage wh