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Differences in HLA-D region antigen expression on alloreactive T lymphocyte clones

✍ Scribed by Hackbarth, Susan; Zeevi, Adriana; Duquesnoy, Rene J.

Book ID
122005640
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
78 KB
Volume
5
Category
Article
ISSN
0198-8859

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T cells specific for different antigens
T cells specific for different antigens express different HLA-D region products
✍ Dolores J. Schendel; Judith P. Johnson πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 597 KB

T cell lines and clones were analyzed for surface expression of Ia antigens using monoclonal antibodies (mAb) that detect monomorphic and polymorphic epitopes on Ia molecules encoded by the HLA-DR and HLA-DQ gene clusters. All mAb bound to B lymphocytes or lymphoblastoid cell lines of the same indiv