DIFFERENCES IN GROWTH REGULATION OF NORMAL AND TUMOR CELLS
โ Scribed by Arthur B. Pardee; Judith Campisi; Robert G. Croy
- Book ID
- 118720261
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 551 KB
- Volume
- 397
- Category
- Article
- ISSN
- 0890-6564
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Metabolic studies in tumor cells have indicated that bioenergetic regulatory mechanisms geared to acute changes in oxygen availability are abnormal. In the present studies we have examined bioenergetic adaptations to chronic oxygen depletion in culture maintained tumor cells in comparison to normal
Facilitated tumor growth was observed in syngeneic animals after the subcutaneous inoculation of these animals with normal syngeneic spleen cells a n d tumor cells previously mixed in vitro. T u m o r incidence, latency, a n d growth rate appear quantitatively directly related to the ratio of spleen
Many cell types will grow when attached to a rigid surface but not in suspension, a phenomenon termed " anchorage dependence ". Anchorage dependence can be studied by incorporating solid particles of varying size into gels. It has been found that colonies will form on glass fibrils 500 p in length,