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Differences in Frequency of ERG Oncoprotein Expression Between Index Tumors of Caucasian and African American Patients With Prostate Cancer

✍ Scribed by Philip Rosen; David Pfister; Denise Young; Gyorgy Petrovics; Yongmei Chen; Jennifer Cullen; Diana Böhm; Sven Perner; Albert Dobi; David G. McLeod; Isabell A. Sesterhenn; Shiv Srivastava


Book ID
116955520
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
836 KB
Volume
80
Category
Article
ISSN
0090-4295

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Ethnic group-related differences in CpG
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## Abstract The incidence and mortality of prostate cancer (PC) is approximately 2‐fold higher among African‐Americans as compared to Caucasians and very low in Asian. We hypothesize that inactivation of __GSTP1__ genes through CpG methylation plays a role in the pathogenesis of PC, and its ability