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Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat

✍ Scribed by S. E. Hemby; Conchita Co; Timothy R. Koves; James E. Smith; Steven I. Dworkin


Publisher
Springer
Year
1997
Tongue
English
Weight
349 KB
Volume
133
Category
Article
ISSN
0033-3158

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Basal extracellular dopamine is decrease
✍ L. H. Parsons; A. D. Smith; Dr. J. B. Justice Jr. πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 743 KB

Rats were treated for 10 days with cocaine (20 mgkg, i.p.1 followed by either 1 or 10 days of abstinence. On the test day a microdialysis method was performed in which dopamine (DA) was added to the perfusate at concentrations above and below the expected extracellular concentration (0,2.5, 5, and 1