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Differences in detoxification of the ultimate carcinogenic dihydrodiol epoxides of benzo[a]pyrene and dibenzo[a,l]pyrene in human Caco-2 cells

✍ Scribed by Hessel, Stefanie; John, Andrea; Seidel, Albrecht; Lampen, Alfonso


Book ID
123157986
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
71 KB
Volume
221
Category
Article
ISSN
0378-4274

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## Abstract Metabolism of the carcinogenic hydrocarbon benzo(a)pyrene (BP) to water and alkali‐soluble products was measured in cultured fibroblast and epithelial cells from human embryos. The alkali‐soluble products represented only a small fraction of BP metabolism. Fibroblasts from different org