Difference in Uptake of Tritiated Thymidine by Myelocytes from Bone Marrow and Spleen in Chronic Myeloid Leukaemia
โ Scribed by Brandt, L.
- Book ID
- 114788500
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Weight
- 209 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0036-553X
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Uptake of "-thymidine into suspension cultures of mouse marrow cells was stimulated by the addition of serum-free conditioned medium harvested from cultures of mouse L-cells. Characterization of the "conditioning factor activity" (CFA) by gel filtration, ion exchange chromatography, velocity sedimen
## Abstract Chronic myeloid leukemia (CML) is a biphasic hematopoietic malignancy associated with a single cytogenetic aberration, the Philadelphia translocation t(9;22)(q34;q11), resulting in the __BCRโABL1__ fusion oncogene. Molecular heterogeneity was recently demonstrated in the form of extensi