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Diethylstilbestrol alters positive and negative selection of T cells in the thymus and modulates T-cell repertoire in the periphery

✍ Scribed by Nicole Brown; Mitzi Nagarkatti; Prakash S. Nagarkatti


Book ID
113923779
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
380 KB
Volume
212
Category
Article
ISSN
0041-008X

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The selection of developing and mature alpha beta T cells, by intrathymic and extra-thymic ligands expressed on cells of hemopoietic and other origins, has been studied in a variety of systems. These experiments have increased our knowledge of the selection of alpha beta T cells in the thymus, in th