𝔖 Bobbio Scriptorium
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Diethyl pyrocarbonate: An examination of its properties in buffered solutions with a new assay technique

✍ Scribed by Shelby L. Berger


Book ID
102982170
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
559 KB
Volume
67
Category
Article
ISSN
0003-2697

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✦ Synopsis


Two assay systems for diethyl pyrocarbonate are described. The first is a spectrophotometric method that makes use of the rapid reaction with the colored compound, 5-thio-2-nitrobenzoate, to form a colorless product. The second is based on the inactivation of lactate dehydrogenase and, unlike the first. can be used in the presence of thiols. The rate of decomposition of diethyl pyrocarbonate has. been studied in several buffers at different pH values.