Diethyl acetonedicarboxylate — a precursor for the synthesis of new substituted 4-aminoquinolines and fused 4-aminopyridines
✍ Scribed by T. Charvát; M. Potáček; J. Marek
- Publisher
- Springer Vienna
- Year
- 1995
- Tongue
- English
- Weight
- 442 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0026-9247
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The electrophilic properties of the 4H-imidazoles 1 and their protonated derivatives 2 permit the introduction of nucleophilic building blocks, as illustrated by reactions of 1 with selected amines. Depending on the nature of the amine and the substituents R 1 on the heterocycle 1, single (3) or dou
## Abstract A simple and convenient method is developed for the synthesis of new O,O‐diethyl O‐(substituted tetrazolo[1,5‐a]quinolin‐4‐yl)methyl phosphorothioates, which has been synthesized for the first time from tetrazolo[1,5‐a] quinolines via tetrazolo[1,5‐a]quinolin‐4‐ylmethanol derivatives. T