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Dietary α-linolenate suppresses endotoxin-induced platelet-activating factor production in rat kidney

✍ Scribed by Kentaro Oh-hashi; Tetsuya Takahashi; Akiko Tanabe; Shiro Watanabe; Harumi Okuyama

Book ID
107489827
Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
109 KB
Volume
34
Category
Article
ISSN
0024-4201

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Excessive nitric oxide (NO) generated by hepatic cells in response to lipopolysaccharide (LPS) and inflammatory substances (e.g., platelet-activating factor [PAF]) is a key contributor to the pathophysiological outcomes observed in the liver during sepsis. In rats subjected to liver-focused endotoxe