Dietary carcinogens and the risk for glioma and meningioma in Germany
✍ Scribed by Heiner Boeing; Brigitte Schlehofer; Maria Blettner; Jürgen Wahrendorf
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- French
- Weight
- 648 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
A population‐based case‐control study was performed in South‐West Germany in 1987/88 with 115 histological confirmed glioma and 81 meningioma cases and 418 randomly selected controls. On the basis of information from a foodfrequency questionnaire and questions on food preparation and food supply, the role of dietary carcinogens, in particular N‐nitroso compounds or their precursors, on risk for glioma and meningioma were analyzed by multiple logistic regression. Eleven food groups were investigated. The intake of processed meat was significantly associated with an increased risk of glioma. The intake of any food group was not significantly related to meningioma risk. Among single meat products, a significantly higher risk of glioma was found for cooked ham, processed pork meat and fried bacon. For the consumption of 3 N‐nitrosamines, assessed from the intake of processed meat and cheese, significant positive relations to glioma risk were found. These N‐nitrosamines were also related to meningioma risk, although to a less pronounced extent. The risk for occurrence of glioma was significantly increased for those using vegetable fat frequently for deep frying, as compared with non‐users. For the dietary intake of nitrate, nitrite, vitamin C, specific alcoholic beverages, total alcohol, and water from a non‐central supply, no elevated risk was found in this study.
📜 SIMILAR VOLUMES
## Abstract The human telomerase reverse transcriptase (__hTERT__) gene is upregulated in a majority of malignant tumours. A variable tandem repeat, MNS16A, has been reported to be of functional significance for __hTERT__ expression. Published data on the clinical relevance of MNS16A variants in br
In a population-based case-control study of 416 incident gliomas in adults carried out in Melbourne, Australia, between I987 and I99 I, 409 age-sex-matched case-control pairs (243 male and I66 female) had adequate data available to examine associations between the dietary intake of N-nitroso compoun
Background: Some dietary foods are considered protective (vegetables and fruits), whereas others (fatty foods) are thought to enhance the risk for Crohn's disease (CD). The evidence, however, is inconsistent. ## Methods: We postulated that specific dietary patterns may influence the risk for CD. A