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Diels-Alder reaction of heterocyclic azadienes. I. Thermal cycloaddition of 1,2,4-triazine with enamines: simple preparation of substituted pyridines

✍ Scribed by Boger, Dale L.; Panek, James S.


Book ID
121199713
Publisher
American Chemical Society
Year
1981
Tongue
English
Weight
546 KB
Volume
46
Category
Article
ISSN
0022-3263

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Novel intramolecular diels-alder reactio
✍ Edward C. Taylor; John E. Macor πŸ“‚ Article πŸ“… 1985 πŸ› Elsevier Science 🌐 French βš– 191 KB

Alkylation of 1,2,4-triazine-6-thiones with 4-iodobutyne, followed by oxidation to the sulfoxide and intramolecular cycloaddition (at room temperature), gives 2,3-dihydrothieno[2,3-c]pyridines, which are readily dehydrated with acetic anhydride to thieno[2,3\_c]pyridines. The same series of reactio