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Diels-alder reaction: New antimicrobial pyrazolo-chroman derivatives

✍ Scribed by F. M. Abd el Latif; A. S. Maghraby; M. A. Barsy; M. Z. A. Badr

Publisher: Wiley (John Wiley & Sons)
Year: 2007
Tongue: English
Weight: 223 KB
Volume: 56
Category: Article
ISSN: 0268-2575
DOI: 10.1002/jctb.280560205

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✦ Synopsis

Pyrazolo-[2,3-d]-chroman dione derivatives were obtained via Diels-Alder reaction of pyrazolone arylidenes and 1,4-benzoquinone. The reaction rate and its yield have been found to be solvent and time dependent. The evaluation of the bactericidal and fungicidal screening showed significant inhibition effects against some thermophilic organisms grown and incubated at 55°C.

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