Dielectric analysis in the characterization of amorphous pharmaceutical solids. 1. Molecular mobility in poly(vinylpyrrolidone)–water systems in the glassy state

Molecular mobility-based estimation of t

Molecular mobility-based estimation of the crystallization rates of amorphous nifedipine and phenobarbital in poly(vinylpyrrolidone) solid dispersions

✍ Yukio Aso; Sumie Yoshioka; Shigeo Kojima 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 160 KB

The overall crystallization rates and mean relaxation times of amorphous nifedipine and phenobarbital in the presence of poly(vinylpyrrolidone) (PVP) were determined at various temperatures to gain further insight into the effect of molecular mobility on the crystallization rates of amorphous drugs