Die Struktur des Anhydro-isocalebassin-methyläthers; Säurekatalysierte Umlagerungen des Curare-Alkaloids C-Calebassin. 60. Mitteilung über Calebassen-Alkaloide [1]
✍ Scribed by K. W. Gemmell; J. Monteath Robertson; G. A. Sim; Karl Bernauer; A. Guggisberg; M. Hesse; H. Schmid; P. Karrer
- Publisher
- John Wiley and Sons
- Year
- 1969
- Tongue
- German
- Weight
- 812 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Sul?zmai.y. Treatment of the Calebash alkaloid C-calebassine (l), C,PH48N40,++. 2 X-, with hot mineral acid yielded the anhydro-isocalebassine acid adduct 3H, with the formula C,H,,N,O+ ++ ' 3 X-. H,O. This mas converted into anhydro-isocalebassine methyl ether salts (4) C,,H,,N,O I-+. 2 X-. H,O with alkaline dimethyl sulphate. A total X-ray analysis of the orthorhonibic diiodidc led t o formula 4. The conversion of C-calebassine (1) into 4 involvcs a radical change in the central part of the molecule.
The structure of the acid adduct 3H can be deduced from the structure of 4.