The conversion of bicyclo [10.3.0]-1,12-epoxy-13-pentadecanone into 4-cyclopentadecyne-1-one, effected by 9-tolylsulfonylhydrazine under mild conditions and in high yield, provides an example of a new fragmentation reaction. Organisch-chemisches Laboratorium der Eidg. Technischen Hochschule, Zurich
Die biologische Oxydation von Fettsäuren mit Dreifachbindung
✍ Scribed by Karl Bernhard; Urs Gloor
- Publisher
- John Wiley and Sons
- Year
- 1953
- Tongue
- German
- Weight
- 272 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
By feeding of stearolic acid, stearol‐alcohol, behenolic acid and hendecynoic acid to dogs we were able to prove the formation of azelaic acid and, therefore, the splitting of the triple bond.
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## Treatment of steroid 20-cyanohydrins under conditions of the hypoiodite reaction The structure proofs of the products are given and examples which show the generates 18-cyano-20-0x0 compounds by a I, +migration oi the cyan0 group. general character of this new type of radical rearrangement are
**Metabolism of Acetylenic Monocarboxylic and Dicarboxylic Acids** Feeding of acetylenic monoacids with chain length of 11 to 18 C‐atoms to rats led to excretion of dicarboxylic acids with retained triple bonds. 10‐Octadecynoic acid led to the formation of metabolites with even and odd number of C‐