Synthesis of didemnolines A-D, N9-substi
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Robert W Schumacher; Bradley S Davidson
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Article
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1999
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Elsevier Science
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French
⚖ 626 KB
Didenmolines A-D (1-4) were synthesized and their suuctures were confirmed through comparisons of data for the synthetic material with those obtained for natural 1-4. The synthesis of didenmolines A (1) and C (3) involved the coupling of 1-[(benzyloxy)methyl]-4-chloromethyl-5-(thiomethyl)imidazole (