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Didemnin B Induces Cell Death by Apoptosis: The Fastest Induction of Apoptosis Ever Described

โœ Scribed by D.R. Grubb; E.J. Wolvetang; A. Lawen

Book ID
115577500
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
386 KB
Volume
215
Category
Article
ISSN
0006-291X

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โœ Karina L. Johnson; David R. Grubb; Alfons Lawen ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 171 KB ๐Ÿ‘ 2 views

Caspases have been implicated in the induction of apoptosis in most systems studied. The importance of caspases for apoptosis was further investigated using the system of didemnin B-induced apoptosis. We found that benzyloxycarbonyl-VAD-fluoromethylketone, a general caspase inhibitor, inhibits didem