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Diclofenac not more effective than acetaminophen in patients with mild knee osteoarthritis: results of a randomized controlled trial in primary care with a 12-week follow-up

✍ Scribed by S.P. Verkleij; P.A. Luijsterburg; B.W. Koes; A.M. Bohnen; S.M. Bierma-Zeinstra

Book ID: 113733695
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 389 KB
Volume: 20
Category: Article
ISSN: 1063-4584
DOI: 10.1016/j.joca.2012.02.259

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## Abstract ## Objective To compare the efficacy and tolerability of the novel cyclooxygenase 2‐selective inhibitor lumiracoxib with placebo and diclofenac in osteoarthritis (OA). ## Methods Adults (n = 583) with knee or hip OA were randomized to receive for 4 weeks lumiracoxib 50, 100, or 200 m