Dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium(II): an effective catalyst for cross-coupling reaction of a secondary alkyl grignard reagent with organic halides
✍ Scribed by Tamio Hayashi; Mitsuo Konishi; Makoto Kumada
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- French
- Weight
- 260 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Swmnary: Dichloro[l,l~-bis(diphenylphosphino)ferrocene]palladium(II) was found to be an effective catalyst for the cross-coupling reaction of see-butylmagnesium chloride with bromobenzene, B-bromostyrene, and Z-bromopropene to give the corresponding see-butyl derivatives in exceedingly high yields.
Phosphine-palladium complexes are known' to catalyze the cross-coupling reaction of aromatic and alkenyl halides with organometallics, such as Grignard reagents,* organo-zinc,3j2e -aluminum,4~2e and -zirconium5 compounds. Of the palladium complexes, tetrakis(triphenylphosphine)palladium(O) has received the most extensive study and proved to be an effective catalyst.