In the present study, we investigated whether the activation of protein kinase C (PKC) and extracellular signal-regulated kinase 1/2 (Erk1/2) are involved in the induction of MMP-9 in lipopolysaccharide (LPS)-stimulated primary astrocytes. The expression of MMP-9 but not MMP-2 was increased by LPS.
Dicarbonyl-mediated protein modifications affect matrix metalloproteinase (MMP) activity
✍ Scribed by B. Bartling; M. Desole; R.-E. Silber; A. Simm
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 266 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0948-6704
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