Dibutyryl-cyclic AMP inhibits cholesterol esterification in J 774 monocyte-like cells

The liver metabolite S-422 of the hypoli

The liver metabolite S-422 of the hypolipidaemic drug benfluorex decreases cholesterol esterification in fibroblasts and monocyte-like cells

✍ J. C. Mazière; C. Mazière; M. Auclair; L. Mora; O. Arnaud 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 702 KB

The effects of S-422 (1-(3-trifluoromethylphenyl)-2-[N-(2-hydroxyethyl) amino] propane), an hepatic metabolite of the hypolipidaemic drug Benfluorex, on lipid metabolism have been investigated in two experimental models: in human fetal lung fibroblasts, for study of the apo B/E receptor-mediated reg