The GAS1 gene product induces growth arrest through a p53-dependent mechanism. To investigate whether GAS1 is a tumor suppressor gene, we transfected GAS1-negative human tumor cells with GAS1 plasmids and analyzed growth characteristics of stable transfectants. When a constitutively expressing GAS1
Diazoniapolycyclic Ions Inhibit the Activity of Topoisomerase I and the Growth of Certain Tumor Cell Lines
β Scribed by Serena Basili; Giuseppe Basso; Anita Faccio; Anton Granzhan; Heiko Ihmels; Stefano Moro; Giampietro Viola
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 701 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1860-7179
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