𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Diazepam tolerance and withdrawal assessed in an animal model of subjective drug effects

✍ Scribed by Michael W. Emmett-Oglesby; Dian A. Mathis; Harbans Lal

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
851 KB
Volume
11
Category
Article
ISSN
0272-4391

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Tolerance to the benzodiazepine diazepam
Tolerance to the benzodiazepine diazepam in an animal model of anxiolytic activity
✍ D. N. Stephens; H. H. Schneider πŸ“‚ Article πŸ“… 1985 πŸ› Springer 🌐 English βš– 649 KB

The antipunishment properties of diazepam (DZP) were investigated in mice treated acutely, or following nine daily treatments with either DZP (5 mg/kg, PO) or its vehicle. Acutely, or following chronic vehicle treatment, DZP produced a dose-related increase in activity punished by footshock. Followi

Chronic diazepam treatment: Effect of do
Chronic diazepam treatment: Effect of dose on development of tolerance and incidence of withdrawal in an animal test of anxiety
✍ E. Sandra πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 384 KB

The effect of the treatment dose of diazepam was assessed on the rate of development of tolerance to diazepam's effects on rat behaviour in the elevated plus-maze test of anxiety. Tolerance developed more rapidly when treatment was with the higher dose: after 14 days when rats were given 2.5mg/kg/da

Extinction of drug- and withdrawal-paire
Extinction of drug- and withdrawal-paired cues in animal models: Relevance to the treatment of addiction
✍ Karyn M. Myers; William A. Carlezon Jr. πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 429 KB

Conditioned drug craving and withdrawal elicited by cues paired with drug use or acute withdrawal are among the many factors contributing to compulsive drug taking. Understanding how to stop these cues from having these effects is a major goal of addiction research. Extinction is a form of learning