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Diazapolycyclic compounds. XVI. Nmr stereochemical studies on the acid-catalyzed oxirane ring-opening reactions of unsubstituted, 2-methyland 2,3-dimethyl- substituted 2,3-epoxy-4a,12a-diaza-1,2,3,4,4a,5,12,12a-octahydronaphthacene-5,12-diones

✍ Scribed by F. Gómez Contreras; P. Navarro


Book ID
112125746
Publisher
Journal of Heterocyclic Chemistry
Year
1979
Tongue
English
Weight
453 KB
Volume
16
Category
Article
ISSN
0022-152X

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## Abstract By heating 2‐chloromethyl‐3,‐5‐dimethyl‐4‐methoxypyridine **(1)** either neat or in solution methoxy group cleavage was achieved, followed by dimerisation to poorly soluble 6,12‐dihydro‐1,3,7,9‐tetramethyl‐5__H__,11__H__‐dipyrido[1,2‐a:1′,2′‐d]pyrazine‐2,8‐dione **(3)** in almost quanti