Synthesis of 1,6-Dideoxynojirimycin, 1,6
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Albert Defoin; Hervรฉ Sarazin; Jacques Streith
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Article
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1996
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John Wiley and Sons
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German
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## Abstract Asymmetric __DielsโAlder__ reaction of sorbaldehyde __O__โmethyloxime 1d with chiral chloronitroso derivative 2 of Dโmannose, followed by osmylation of the primary cycloadduct, led to diol 6a with excellent enantioselectivity (ee > 99%; __Scheme 1__). Catalytic hydrogenolysis of 6a gave