Diastereoselectivity in Organometallic Additions to the Carbonyl Group of Protected Erythrulose Derivatives
✍ Scribed by Marco, J. Alberto; Carda, Miguel; González, Florenci; Rodríguez, Santiago; Castillo, Encarna; Murga, Juan
- Book ID
- 126130621
- Publisher
- American Chemical Society
- Year
- 1998
- Tongue
- English
- Weight
- 127 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0022-3263
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Boron aldol additions of l-O-silylated 3,4-di-O-benzyl-and 3,4-di-O-benzoyl-L-erythrulose and achiral aldehydes using dicyclohexylboron chloride have been investigated. The dibenzyl derivative gave syn/syn stereoisomers with high stereoselectivity, whereas the dibenzoyl derivative gave synlanti ster
Boron Aldol Additions with Erythrulose Derivatives: Dependence of Stereoselectivity on the Type of Protecting Group. -The boron aldol addition of di-O-benzyl-or di-O-benzoyl protected erythruloses and achiral aldehydes give either syn/syn or syn/anti stereoisomers with high stereoselectivity. It is