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Diastereoselective Ultrasonically Induced Zinc—Copper Conjugate Addition to Chiral α,β-Unsaturated Carbonyl Systems in Aqueous Media.

✍ Scribed by Rosa Ma. Suarez; Jose Perez Sestelo; Luis A. Sarandeses


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
33
Category
Article
ISSN
0931-7597

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Diastereoselective Conjugate Addition to
✍ Rosa M. Suárez; José Pérez Sestelo; Luis A. Sarandeses 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 213 KB

The stereoselectivity of the ultrasonically induced zinc--copper conjugate addition of iodides to chiral alpha,beta-unsaturated carbonyl systems under aqueous conditions was studied. Alkyl iodides add diastereoselectively to methylenedioxolanone 1 and methyleneoxazolidinone 2 to afford the 1,4-addit