AbstractÐThis paper describes a new general approach towards functionalized piperidine alkaloids, based on the stereo-and regioselective palladium(0)-catalyzed nucleophilic ring-opening of vinyl epoxides by nitrogen nucleophiles. The latter reaction provides access to stereo-de®ned anti and syn amin
Diastereoselective total synthesis of 3,6-disubstituted piperidine alkaloids, (3R,6S)-epi-pseudoconhydrine and (3R,6R)-pseudoconhydrine
✍ Scribed by Khobare, Sandip R.; Gajare, Vikas S.; Jammula, Subbarao; Syam Kumar, U.K.; Murthy, Y.L.N.
- Book ID
- 120260032
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- French
- Weight
- 646 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0040-4039
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
A highly efficient, flexible and diastereoselective route to all-cis-2,6disubstituted 3-piperidinols has been accomplished. The key component of the synthesis is a chiral I]-hydroxyester, which was obtained by iipase catalyzed kinetic resolution. Based on this starting material, diastereoselective a