Diastereoselective synthesis of γ-dispiroiminolactone bearing naphthalene or bipyridine pendant groups
✍ Scribed by Malek T. Maghsoodlou; Nourollah Hazeri; Sayyed M. Habibi-Khorassani; Morteza Ziyaadini; Ghasem Marandi; Khatereh Khandan-Barani; Pouneh Ebrahimi; Faramarz Rostami Charati; Alexandre Sobolev; Mohamed Makha
- Book ID
- 102341085
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2009
- Tongue
- English
- Weight
- 167 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0022-152X
- DOI
- 10.1002/jhet.164
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
magnified image
Diastereoselective γ‐dispiroiminolactone products 4a, 4b, 4c, 4d, 4e, 4f, 4g, 4h, 4i, 4j, 4k, 4l, 4m were obtained from a condensation of the highly reactive 1:1 intermediate of isocyanides and acetylenic esters with aromatic α‐dicarbonyls compounds 3a, b. J. Heterocyclic Chem., (2009).
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The synthesis of benzene-1, 4-bis(carboxamido-N,N-bis(acetyldiglicylglycinamide-N 0 -ethyl-2-N 00 -carbomoyl-(3,7-dimethoxy-2-naphthalene) by the method allowing one to avoid its tedious purification and unsuccessful attempts to obtain its quadruple complexes with native cyclodextrins are described.